Table 2.
IFN-γ, TNF-α, IL-1β, IL-5, IL-13 and MIF from subjects’s PBMCs
| Zn (μM) | IFN-γ (pg/mL) | TNF-α (pg/mL) | IL-1β (pg/mL) | IL-5 (pg/mL) | IL-13 (pg/mL) | MIF (ng/mL) |
|---|---|---|---|---|---|---|
| Patient 1 | ||||||
| 0 | 1.7 | 1.4 | 1.3 | 0.3 | <0.2 | 1.5 |
| 5 | 5.2 | 38.2 | 1.6 | 0.5 | 1.3 | 1.5 |
| 50 | 11.6 | 42.8 | 18.9 | 2.6 | 7.9 | 2.8 |
| 10 | 19.3 | 71.3 | 22.5 | 5.8 | 18.7 | 7.8 |
| Patient 2 | ||||||
| 0 | 1.3 | <0.01 | 0.8 | <0.2 | <0.2 | 2.1 |
| 5 | 10.5 | 30.2 | 1.0 | <0.2 | 3.6 | 3.2 |
| 50 | 17.2 | 50.5 | 20.3 | 3.7 | 10.6 | 5.4 |
| 100 | 25.3 | 88.8 | 24.2 | 6.9 | 16.3 | 8.0 |
| Patient 3 | ||||||
| 0 | 0.9 | 0.3 | 1.2 | <0.2 | 0.3 | 5.3 |
| 50 | 9.8 | 15.2 | 1.7 | 0.3 | 5.5 | 6.8 |
| 50 | 12.3 | 13.8 | 20.1 | 3.8 | 14.6 | 6.2 |
| 100 | 20.5 | 19.1 | 26.6 | 9.2 | 2.3 | 6.9 |
| Patient 4 | ||||||
| 0 | 1.6 | <0.01 | 0.9 | <0.2 | 0.4 | 0.8 |
| 5 | 8.3 | 12.1 | 0.8 | 0.8 | 9.6 | 1.2 |
| 50 | 15.5 | 13.2 | 12.3 | 2.1 | 14.5 | 3.8 |
| 100 | 20.3 | 15.7 | 18.9 | 6.3 | 20.3 | 9.7 |
| Patient 5 | ||||||
| 0 | 0.7 | 0.4 | <0.04 | <0.2 | <0.2 | 1.3 |
| 5 | 1.0 | 5.5 | 0.8 | 1.0 | <0.2 | 2.4 |
| 50 | 5.6 | 11.2 | 18.6 | 11.5 | 13.2 | 3.2 |
| 100 | 13.3 | 35.0 | 23.5 | 20.7 | 19.7 | 7.0 |
| Control 1 | ||||||
| 0 | 1.2 | <0.01 | 0.5 | <0.2 | 0.9 | 1.1 |
| 5 | 1.6 | <0.01 | 0.9 | 0.3 | 1.0 | 1.3 |
| 50 | 6.3 | <0.01 | 1.5 | 0.5 | 1.3 | 3.8 |
| 100 | 8.5 | <0.01 | 2.3 | 0.5 | 1.5 | 2.6 |
| Control 2 | ||||||
| 0 | 1.7 | <0.01 | 1.1 | <0.2 | 0.5 | 0.4 |
| 5 | 3.6 | <0.01 | 1.5 | 0.4 | 0.8 | 0.3 |
| 50 | 4.9 | <0.01 | 1.8 | 0.4 | 0.8 | 0.8 |
| 100 | 6.3 | <0.01 | 1.8 | 0.8 | 1.2 | 0.6 |
| Control 3 | ||||||
| 0 | 1.8 | <0.01 | 0.8 | <0.2 | 0.6 | 0.2 |
| 5 | 3.2 | <0.01 | 1.1 | <0.2 | 0.6 | 1.1 |
| 50 | 5.1 | <0.01 | 1.3 | <0.2 | 1.0 | 0.4 |
| 100 | 7.2 | <0.01 | 1.6 | 0.4 | 1.1 | 1.1 |
| Control 4 | ||||||
| 0 | 0.9 | <0.01 | 1.0 | 0.1 | 0.8 | 1.4 |
| 5 | 2.6 | <0.01 | 0.9 | 0.1 | 0.9 | 1.3 |
| 50 | 4.9 | <0.01 | 1.1 | 0.1 | 0.9 | 1.0 |
| 100 | 7.8 | <0.01 | 1.8 | 0.4 | 1.2 | 0.9 |
| Control 5 | ||||||
| 0 | 0.3 | <0.01 | <0.04 | <0.2 | <0.2 | 0.3 |
| 5 | 0.3 | <0.01 | <0.04 | 0.3 | <0.2 | 0.5 |
| 50 | 0.7 | <0.01 | <0.04 | 1.0 | <0.2 | 0.6 |
| 100 | 1.6 | <0.01 | 0.4 | 0.3 | <0.2 | 0.3 |