Table 1.
Results of the cytotoxicity assay. Each experiment has been repeated twice in triplicate and results are summarized as mean and standard deviation (SD) of IC50 (nM)
| Mean Paclitaxel | Mean Paclitaxel | SD Paclitaxel | Mean Cisplatin | Mean Cisplatin | SD Cisplatin | |
|---|---|---|---|---|---|---|
| A2780wt | 1.40 | 0.14 | 241.00 | 22.63 | ||
| NEK6_clone10 | 3.60 | 0.42 | 281.00 | 2.83 | ||
| NEK6_clone17 | 2.95 | 1.06 | 374.00 | 33.94 | ||
| NEK6_clone24 | 1.60 | 0.00 | 421.50 | 2.12 | ||
| NEK6_clone3 | 3.50 | 0.57 | 431.00 | 9.90 | ||
| NEK6_pool | 3.50 | 0.42 | 502.50 | 24.75 | ||
| PUSE_clone_18 | 1.98 | 0.18 | 226.50 | 0.71 | ||
| PUSE_clone_19 | 1.85 | 0.21 | 276.00 | 57.98 | ||
| PUSE_clone_21 | 2.63 | 0.11 | 219.00 | 155.56 | ||
| PUSE_clone_23 | 2.61 | 0.55 | 239.50 | 38.89 | ||
| PUSE_pool | 1.87 | 0.16 | 247.50 | 45.96 | ||
| Hey wt | 7.65 | 1.20 | 3365.00 | 162.63 | ||
| SiC_clone_11 | 8.80 | 0.14 | 2591.00 | 169.71 | ||
| SiC_clone_15 | 6.05 | 3.32 | 3549.50 | 579.12 | ||
| SiC_pool | 8.10 | 0.42 | 2783.50 | 94.05 | ||
| SiNEK6_clone23 | 2.90 | 0.28 | 1304.50 | 317.49 | ||
| SiNEK6_clone7 | 5.30 | 5.80 | 1133.50 | 60.10 | ||
| SiNEK6_pool | 6.15 | 0.35 | 1737.00 | 145.66 |