Table 1.
Correlations between Twist expression and clinicopathological characteristics in colorectal cancer patients
| Characteristics | Total (n=95) | Twist expression | P-value | |
|---|---|---|---|---|
|
| ||||
| n (%) | Negative | Positive | ||
| Sex | 0.099* | |||
| Male | 58 (61.1) | 17 (29.3) | 41 (70.7) | |
| Female | 37 (38.9) | 17 (45.9) | 20 (54.1) | |
| Age (y) | 0.515* | |||
| ≤60 | 49 (51.6) | 14 (28.6) | 35 (71.4) | |
| >60 | 46 (48.4) | 16 (34.8) | 30 (65.2) | |
| Histological type | 0.076* | |||
| Tubular | 65 (68.4) | 19 (29.2) | 46 (70.8) | |
| Mucinous | 15 (15.8) | 9 (60.0) | 6 (40.0) | |
| Papillary | 15 (15.8) | 6 (40.0) | 9 (60.0) | |
| Histological grade | 0.004* | |||
| G1 | 17 (17.9) | 12 (70.6) | 5 (29.4) | |
| G2 | 64 (67.4) | 18 (28.1) | 46 (71.9) | |
| G3 | 14 (14.7) | 4 (28.6) | 10 (71.4) | |
| T-stage | 0.033* | |||
| T1-2 | 15 (15.8) | 9 (60.0) | 6 (40.0) | |
| T3-4 | 80 (84.2) | 25 (31.3) | 55 (68.8) | |
| N-stage | 0.000* | |||
| N0 | 51 (53.7) | 28 (54.9) | 23 (45.1) | |
| N1-2 | 44 (46.3) | 6 (13.6) | 38 (86.4) | |
| M-stage | 0.040* | |||
| M0 | 83 (87.4) | 40 (48.2) | 43 (51.8) | |
| M1 | 12 (12.6) | 2 (16.7) | 10 (83.3) | |
| Tumor differentiation | 1.000** | |||
| Moderate/Well | 86 (90.5) | 31 (36.0) | 55 (64.0) | |
| Poor/other | 9 (9.5) | 3 (33.3) | 6 (66.7) | |
| Colorectal cancer type | 0.940* | |||
| Colon cancer | 61 (64.2) | 22 (36.1) | 39 (63.9) | |
| Rectal cancer | 34 (35.8) | 12 (35.3) | 22 (64.7) | |
| TNM stage | 0.002* | |||
| I-II | 41 (43.2) | 22(53.7) | 19 (46.3) | |
| III-IV | 54 (56.8) | 12 (22.2) | 42 (77.8) | |
| Recurrence | 0.023* | |||
| Yes | 17 (17.9) | 2 (11.8) | 15 (88.2) | |
| No | 78 (82.1) | 32 (41.0) | 46 (59.0) | |
*
Pearson Chi-square test.
**
Continuity Correction test.