Table 2.
Association between FOXC2 expression and clinicopathological factors in colon cancers (n=185)
| Variable | n | FOXC2 Expression | χ2 Value | P value | |
|---|---|---|---|---|---|
|
|
|||||
| Negative/Low | High | ||||
| Gender | 0.001 | 0.974 | |||
| Male | 82 | 40 | 42 | ||
| Female | 103 | 50 | 53 | ||
| Age | 1.082 | 0.292 | |||
| ≤60 | 61 | 33 | 28 | ||
| >60 | 124 | 57 | 67 | ||
| T category | 11.096 | 0.011a | |||
| T1 | 7 | 7 | 0 | ||
| T2 | 23 | 14 | 9 | ||
| T3 | 73 | 36 | 37 | ||
| T4 | 82 | 33 | 49 | ||
| LNM | 12.622 | <0.001 | |||
| Negative | 107 | 64 | 43 | ||
| Positive | 78 | 26 | 52 | ||
| AJCC stage | 12.524 | <0.001 | |||
| I/II | 105 | 63 | 42 | ||
| III | 80 | 27 | 53 | ||
| Pathological grading | 1.182 | 0.277 | |||
| High/Moderate | 166 | 83 | 83 | ||
| Poor/undifferentiation | 19 | 7 | 12 | ||
| Lymphovascular invasion | 4.346 | 0.037 | |||
| Negative | 174 | 88 | 86 | ||
| Positive | 11 | 2 | 9 | ||
| Ki67 | 12.265 | <0.001 | |||
| Negative | 52 | 36 | 16 | ||
| Positive | 133 | 54 | 79 | ||
Fisher’s exact test.