Table 4.
Correlations between clinicopathological parameters and survival in patients with rectal caner
| Parameters | 5-year DFS (%) | P value | 5-year OS (%) | P value |
|---|---|---|---|---|
| Age | ||||
| <65 | 59% | 0.149 | 71% | 0.238 |
| ≥ 65 | 43% | 62% | ||
| Sex | ||||
| Male | 56% | 0.160 | 70% | 0.302 |
| Female | 44% | 62% | ||
| Histology | ||||
| Differentiated | 51% | 0.711 | 69% | 0.622 |
| Undifferentiated | 50% | 65% | ||
| White cell count | ||||
| <4 (×109/L) | 43% | 0.390 | 58% | 0.323 |
| 4-8 (×109/L) | 51% | 72% | ||
| > 8 (×109/L) | 56% | 67% | ||
| cT | ||||
| 3 | 56% | 0.033* | 76% | 0.008* |
| 4 | 44% | 55% | ||
| cN | ||||
| Negative | 65% | 0.012* | 81% | 0.014* |
| Positive | 43% | 59% | ||
| Neo-adjuvant therapy | ||||
| Chemotherapy alone | 36% | 0.023* | 70% | 0.128 |
| Radiotherapy alone | 45% | 48% | ||
| Chemo-radiotherapy | 61% | 74% | ||
| TRG | ||||
| Good response | 64% | 0.001* | 81% | 0.001* |
| Poor response | 38% | 54% | ||
| CD3+TILs | ||||
| High | 59% | 0.010* | 75% | 0.019* |
| Low | 40% | 56% | ||
| CD8+ | ||||
| High | 61% | 0.002* | 77% | 0.003* |
| Low | 37% | 54% |
*
Statistically significant.