Table 1.

Most abundant miRNAs in MSC exosomes and cells

Rank	Most represented miRNA in exosomes		Most represented miRNA in cells
	miRNA	rpm ASC exosomes	miRNA	rpm ASC cells
1	miR-486-5p	172,837	miR-21-5p	145,332
2	miR-10a-5p	117,453	miR-22-3p	92,902
3	miR-10b-5p	104,447	miR-10b-5p	82,089
4	miR-191-5p	92,545	miR-222-3p	74,725
5	miR-222-3p	49,405	miR-143-3p	73,794
6	miR-22-3p	37,205	let-7a-5p	71,686
7	let-7a-5p	28,814	miR-10a-5p	44,303
8	miR-21-5p	27,233	miR-92a-3p	33,827
9	miR-127-3p	27,071	let-7f-5p	33,248
10	miR-143-3p	22,579	let-7i-5p	22,624
11	miR-99b-5p	21,471	miR-127-3p	17,303
12	miR-100-5p	18,836	miR-148a-3p	17,109
13	miR-92a-3p	18,217	miR-26a-5p	16,127
14	let-7f-5p	17,589	miR-92b-3p	14,852
15	miR-92b-3p	16,124	miR-21-3p	14,548
16	miR-26a-5p	13,207	miR-221-3p	12,481
17	miR-146a-5p	12,212	miR-16-5p	11,544
18	miR-4485	10,656	miR-100-5p	11,180
19	miR-146b-5p	10,,558	miR-31-5p	9521
20	miR-151a-3p	10,262	miR-411-5p	8051
	miRNA	rpm BMSC exosomes	miRNA	rpm BMSC cells
1	miR-143-3p	124,950	miR-143-3p	185,884
2	miR-10b-5p	103,485	miR-21-5p	150,993
3	miR-486-5p	91,274	miR-22-3p	105,358
4	miR-22-3p	74,730	let-7a-5p	91,387
5	miR-21-5p	47,445	miR-10b-5p	42,729
6	miR-222-3p	46,094	miR-222-3p	38,076
7	miR-191-5p	45,054	miR-27b-3p	35,496
8	miR-100-5p	41,668	let-7f-5p	29,054
9	let-7a-5p	38,486	let-7i-5p	21,993
10	miR-99b-5p	29,011	miR-26a-5p	21,934
11	miR-92a-3p	24,941	miR-100-5p	21,157
12	miR-127-3p	21,319	miR-127-3p	14,836
13	let-7f-5p	21,203	miR-148a-3p	12,789
14	miR-92b-3p	20,938	miR-92b-3p	12,306
15	miR-423-5p	19,807	miR-92a-3p	11,840
16	miR-10a-5p	14,716	miR-191-5p	11,384
17	miR-27b-3p	13,604	miR-21-3p	11,372
18	let-7i-5p	11,997	miR-125b-5p	10,699
19	miR-28-3p	10,554	let-7b-5p	9603
20	miR-125b-5p	10,378	miR-16-5p	9583

miRNAs present only in the list of cellular or in the list of exosomal miRNAs are highlighted in bold

ASC adipose-derived mesenchymal stem cell, BMSC bone marrow-derived mesenchymal stem cell, miRNA microRNA, MSC mesenchymal stem cell, rpm reads per million