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. 2015 Aug 8;17(1):70. doi: 10.1186/s12968-015-0175-4

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© Schär et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Results from Monte Carlo simulations of the TwiST experiment (without spill-over correction) over a range of TR_long (with γ-ATP saturated) and TR_control (control saturation), averaged over a range of k_f from 0.1-0.4 s⁻¹ and T₁ ^intrinsic from 5–9 s. Averages were chosen for a constant total study time of 30 min. a The relative percentage SD in k_f for average choices that led to the smallest error at each TR combination. b The average bias error in k_f, corresponding to the same TR and average combinations as in a) and T₁ ^intrinsic of 7 s. The red dot illustrates the TRs used in the human acquisitions in this study (TR_long = 10s and TR_control = 16 s)