. Author manuscript; available in PMC: 2016 Aug 1.

Published in final edited form as: JACC Heart Fail. 2015 Jul 8;3(8):591–599. doi: 10.1016/j.jchf.2015.03.007

Table 3.

Concentration of Biomarkers for HIV-Infected Participants and Controls

Biomarker	HIV+ (N = 332)	Control (N = 50)	P-value	HIV+ versus Control
Biomarker	HIV+ (N = 332)	Control (N = 50)	P-value	Unadjusted %Estimate	P-value	Adjusted %Estimate^*	P-value
ST2 (ng/ml)	28.5 (23.1, 37.6)	29.2 (23.8, 33.0)	0.34	7.1 (−3.0, 18.2)	0.18	8.8 (−1.1, 19.7)	0.08
NT-proBNP (pg/ml)	38.6 (19.2, 108.3)	17.7 (11.9, 32.2)	<0.001	151.0 (96.7, 220.4)	<0.001	130.2 (82.3. 190.7)	<0.001
GDF-15 (pg/ml)	971 (571, 1805)	336 (263, 431)	<0.001	237.7 (189.5, 293.8)	<0.001	231.5 (183.9, 286.9)	<0.001
hsCRP (mg/L)	2.3 (0.8, 5.6)	1.9 (0.4, 4.5)	0.05	54.9 (6.1, 126.3)	0.02	53.8 (4.7, 126.0)	0.03
IL-6 (pg/ml)	3.1 (1.5, 5.8)	2.3 (1.4, 3.8)	0.06	22.8 (−7.5, 63.1)	0.16	20.3 (−9.6, 60.1)	0.21
Cystatin C (mg/L)	0.78 (0.66, 0.93)	0.61 (0.47, 0.64)	<0.001	39.4 (27.6, 52.3)	<0.001	39.5 (27.6, 52.4)	<0.001
D-Dimer (ng/mL)	231 (147, 389)	183 (114, 265)	0.002	40.3 (18.9, 65.7)	<0.001	36.0 (17.5, 57.4)	<0.001
Detectable hsTnI (ng/ml)	85 (27%)	7 (14%)	0.06	94.6 (11.1, 240.9)	0.02	90.1 (6.4, 239.4)	0.03

Data are presented as Median (IQR) or Percent (95% Confidence Interval)

Adjusted for Age, Gender and Estimated Glomerular Filtration Rate