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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Dev Biol. 2015 Jun 17;405(1):56–70. doi: 10.1016/j.ydbio.2015.06.009

Figure 6. Mesenchymal deletion of Sox9 from developing trachea does not promote expansion of tracheal muscle layer.

Figure 6

Sox9 was deleted using Col2a1Cre mice, resulting in tracheal cartilage agenesis (B,D,F). No expansion of muscle into the ventral mesenchyme of the trachea was observed (D,F). RT-PCR analysis demonstrates that Sox9 mRNA is decreased while Acta2 mRNA was not significantly changed in E14.5 Sox9f/f;Col2a1Cre/+ trachea (G). N=4 **p<0.01.