Table I.

REVIEW OF LITERATURE

Cases	Presentation	Treatment	Outcome
Hochstetler et al [20]	De novo TMA 2 months post kidney-pancreas transplant; new IgM anti-CMV Ab detected Series of 22 patients with de novo TMA after DDRT; 42% developed active CMV infection	IV immunoglobulin	Complete recovery
Jeejeebhoy & Zaltzman [21]	De novo TMA associated with primary CMV disease 6 weeks post transplant	Condition worsened with daily PE but responded to IV Ganciclovir	Complete recovery
Waiser et al [6]	De novo HUS 5 days after patient developed biopsy proven CMV esophagitis	IV Ganciclovir	Complete recovery
Waiser et al [6]	De novo HUS within 3 days after onset of primary CMV disease	IV Ganciclovir	Complete recovery
Olie et al [22]	TMA post transplant in a patient with familial HUS with factor H mutation 10 months post transplant successfully treated. Recurrent TMA with CMV relapse	IV Ganciclovir; PE	Complete recovery
De Keyzer et al [23]	De novo TMA 25 years post transplant in association with CMV esophagitis, gastritis and pneumonitis	Daily PE, IV Ganciclovir, CMVIg and IV foscarnet	Allograft loss; 2nd transplant

The numbers in parenthesis refer to the number in the References