Table 4.
Multivariable Regressions on SF-12 for Lung subjects
| PCS | MCS | |||||
|---|---|---|---|---|---|---|
| Model 1 Lung cancer symptom index |
Model 2 Non-specific cancer symptom index |
Model 3 Non-specific & lung cancer symptom index |
Model 1 Lung cancer symptom index |
Model
2 Non-specific cancer symptom index |
Model 3 Non-specific & lung cancer symptom index |
|
| Model Statistics | ||||||
| Model F-statistic (degrees of freedom) | 33.7 (20,2058) | 24.0 (20,2058) | 37.20 (21,2057) | 13.0 (20,2058) | 23.4 (20,2058) | 24.4 (21,2057) |
| P-value for Whole Model F-statistic | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.001 | <0.001 |
| Full model Adjusted R2 | 0.24 | 0.18 | 0.27 | 0.10 | 0.18 | 0.19 |
| N | 2079 | 2079 | 2079 | 2079 | 2079 | 2079 |
| Model coefficients(p-values) | β | β | β | β | β | Β |
| Age: ref=<65 | ||||||
| 65–74 | 0.06(0.01) | 0.05(0.03) | 0.04(0.08) | 0.07(0.004) | 0.03(0.09) | 0.03(0.13) |
| 75+ | 0.02(0.43) | 0.02(0.34) | 0.003(0.88) | 0.08(0.002) | 0.06(0.01) | 0.05(0.02) |
| Race: ref=White | ||||||
| African American | 0.07(<0.001) | 0.06(0.01) | 0.07(<0.001) | −0.02(0.35) | −0.03(0.14) | −0.03(0.20) |
| Unknown or Other | 0.01(0.54) | 0.004(0.82) | 0.01(0.52) | −0.02(0.37) | −0.02(0.30) | −0.02(0.37) |
| Gender: ref=Male | ||||||
| Female | 0.0003(0.99) | 0.04(0.04) | 0.02(0.36) | −0.06(0.003) | −0.02(0.25) | −0.03(0.11) |
| Marital Status ref=Not Married | ||||||
| Married | 0.04(0.08) | 0.05(0.03) | 0.03(0.19) | 0.03(0.14) | 0.02(0.25) | 0.02(0.44) |
| Education: ref=<High School | ||||||
| High School Graduate | −0.08(0.004) | −0.04(0.22) | −0.08(0.002) | 0.05(0.12) | 0.06(0.03) | 0.04(0.13) |
| Some College | −0.03(0.21) | 0.02(0.48) | −0.04(0.17) | 0.04(0.14) | 0.06(0.03) | 0.04(0.16) |
| College Graduate | −0.04(0.15) | 0.01(0.78) | −0.03(0.14) | 0.01(0.59) | 0.03(0.21) | 0.01(0.55) |
| >College | 0.01(0.69) | 0.05(0.05) | 0.004(0.85) | 0.05(0.05) | 0.06(0.02) | 0.04(0.09) |
| Treatment: ref=Not receiving | ||||||
| Surgery | −0.05(0.03) | 0.01(0.50) | −0.04(0.13) | −0.06(0.03) | −0.02(0.39) | −0.03(0.24) |
| Radiation | −0.05(0.02) | −0.003(<0.001) | −0.05(0.02) | −0.03(0.15) | −0.04(0.06) | −0.03(0.18) |
| Chemotherapy | −0.05(0.02) | 0.04(0.51) | −0.02(0.34) | −0.03(0.32) | 0.03(0.21) | 0.03(0.26) |
| Stage at diagnosis: ref=Stage:0–1 | ||||||
| Stage:2–3 | −0.03(0.34) | −0.02(0.49) | −0.01(0.57) | −0.02(0.54) | −0.002(0.95) | −0.0002(0.99) |
| Stage:4 | −0.09(0.002) | −0.06(0.03) | −0.07(0.01) | −0.08(0.01) | −0.02(0.34) | −0.06(0.04) |
| Stage:unknown | −0.01(0.63) | −0.002(0.90) | −0.01(0.77) | −0.03(0.20) | −0.02(0.95) | −0.02(0.31) |
| Comorbidity: ref=None | ||||||
| One | −0.08(<0.001) | −0.11(<0.001) | −0.07(<0.001) | 0.01(0.55) | 0.001(0.95) | 0.02(0.48) |
| Two+ | −0.07(<0.001) | −0.08(<0.001) | −0.06(0.004) | −0.03(0.26) | −0.02(0.47) | −0.01(0.75) |
| Years since diagnosis | 0.05(0.02) | 0.02(0.30) | 0.03(0.12) | 0.03(0.13) | 0.001(0.97) | 0.004(0.84) |
| Cancer-type specific symptom index (lung cancer)† | −0.42(<0.001) | −0.34(<0.001) | −0.27(<0.001) | −0.14(0.001) | ||
| Non-specific cancer symptom index† | −0.33(<0.001) | −0.20(<0.001) | −0.39(<0.001) | −0.34(<0.001) | ||
β=standardized coefficients; Ref=reference;
†
Higher scores=increasing symptoms.