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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Mol Cancer Ther. 2015 May 29;14(8):1896–1906. doi: 10.1158/1535-7163.MCT-14-0865

Figure 5. TMPRSS2-ERG impairs the recruitment and retention of NHEJ components.

Figure 5

A, Chromatin recruitment of indicated proteins at 0, 30, and 60 min after IR (10 Gy), examined with the corresponding primary antibodies; cell fractionation was performed as described in Materials and Methods. B, XRCC4, Ligase IV, and XLF levels in PC3 and TMPRSS2-ERG-expressing cells at the indicated times following IR. β-actin was used as a loading control. C, Chromatin recruitment of indicated proteins at 0, 30, and 60 min following IR (10 Gy). The data are representative of three independent experiments.