Table 2.
Comparison of clinical features, Bath AS indices, and inflammatory markers in JAS patients with B27-negative and different B27 subtypes.
| HLA-B27 subtype |
Age (y) | Onset age (y) | Disease duration (y) | BASDAI (score) |
BASFI (score) |
ESR (mm/h) |
CRP (mg/L) |
|---|---|---|---|---|---|---|---|
| HLA-B27-negative | 18.09 ± 3.65 (n = 11) |
14.09 ± 2.11 (n = 11) |
4.01 ± 4.39 (n = 11) |
2.05 ± 1.42 (n = 11) |
1.55 (1.21, 3.43 ) (n = 8) |
7.00 (4.00, 9.40) (n = 11) |
1.10 (0.60, 5.00) (n = 7) |
| HLA-B*2704 | 21.79 ± 8.02 (n = 120) |
13.54 ± 2.31 (n = 120) |
8.25 ± 8.06 (n = 120) |
4.22 ± 1.95
*
(n = 112) |
3.00 (1.90, 5.20) (n = 112) |
32.00 (14.00, 48.75)
*
(n = 120) |
18.55 (5.9, 49.78)
*
(n = 120) |
| HLA-B*2705 | 18.36 ± 3.96 (n = 11) |
13.55 ± 1.77 (n = 11) |
4.82 ± 4.46 (n = 11) |
3.61 ± 1.26 (n = 9) |
1.6 (1.00, 4.20) (n = 9) |
14.0 (7.00, 48.00)
*
(n = 11) |
5.80 (1.45, 34.30) (n = 11) |
| HLA-B*2715 | 24.33 ± 6.43 (n = 3) |
9.00 ± 4.00
∗#a
(n = 3) |
15.33 ± 4.16
∗a
(n = 3) |
3.28 ± 2.79 (n = 2) |
1.125 (1.00, 1.25) (n = 2) |
65.00 (4.00, 135.00)
*
(n = 3) |
15.53 (1.50, 113.45) (n = 3) |
Note: (1) data in the table was mean ± standard deviation or median (upper quartile, lower quartile); (2) * comparison between groups of different B27 subtypes and group of B27-negative, P < 0.05; (3) # comparison between HLA-B∗2715 and HLA-B∗2704 group, P < 0.05; (4) a comparison between HLA-B∗2715 and HLA-B∗2705 group, P < 0.05.