Table I.
In vitro assays for research examining the rationale of using specific tests at the onset of ADR.
Genetic assays |
HLA-A (81) |
HLA-B (82) |
HLA-C (83) |
HLA-DR (84) |
HLA-DQ (85) |
Immune-disease associated genes |
T cell differentiation IL2-IL21 (86) |
Signaling CTLA-4 (87) |
Innate immunity IFIH1 (88) |
Cytokines IL7R (24) |
Drug metabolism genes |
CYP34A (58) |
CTP2C9 (59) |
GCLC (61) |
Nrf-2 (62) |