Table 1.

Area under the curve (AUC) in ESA studies

Study	Epo 1000 U/kg	Epo 2500 U/kg	Epo 3500 U/kg	Epo 5000 U/kg	Darbe 2 μg/kg	Darbe 10 μg/kg
Rats1 (Statler et al)	----	----	----	140,331	----	----
Primates2 (Traudt et al)	94,377±5801	----	413,948±39,605	----	----	----
ELBW infants3 (Juul et al)	81,498±7,067	317,881±22,941	----		----	----
Term HIE4 (Wu et al)	131,054±17,083	328,000±61,945	----	----	----	----
Term HIE5 (Baserga et al)	----	----	----	----	26,555 (20,049–35,029)	180,886 (146,568–199,680)

AUC values are (U*h)/L, and are reported as mean ± SD (Traudt and Wu studies) mean ± SEM (Juul), or median (IQR) for (Baserga).

¹reference 13;

²reference 14;

³reference 15;

⁴reference 16;

⁵reference 17