Figure 3. Effects of CR-PsmI on cardiac hypertrophy and function at 24 weeks after mTAC.
T60A-β5 Tg and Ntg littermate mice of 10-week-old were subject to mTAC or sham surgery. A, Gravimetric analyses. For each parameter shown, the difference between Ntg-mTAC and Tg-mTAC groups is not statistically significant (p>0.05). **p<0.01 vs. Ntg sham; n=8 mice/group. B, LV hemodynamics assessments. *p<0.05 vs. Ntg sham and Ntg TAC; n=5 mice/group.