Table 2.
LV pressure-volume relationship at 6 days after sTAC
| NTG Sham | T60A-β5 Sham | NTG sTAC | T60A-β5 sTAC | |
|---|---|---|---|---|
| N | 6 | 6 | 6 | 6 |
|
| ||||
| HR, beats/min | 505±23.6 | 514±22.7 | 554±28.3 | 506±35.6 |
|
| ||||
| Pes, mmHg | 118.3±10.4 | 111.5±2.0 | 166.3±5.3* | 130.4±33.3 |
|
| ||||
| Ves, μl | 10.4±2.9 | 12.0±4.2 | 5.0±1.8* | 32.9±6.7*† |
|
| ||||
| Ped, mmHg | 4.1±2.0 | 3.8±2.8 | 14.8±2.1* | 10.3±1.7*† |
|
| ||||
| Ved, μl | 36.4±6.2 | 38.4±7.6 | 24.8±2.4* | 51.2±8.3*† |
|
| ||||
| SV, μl | 26.0±3.4 | 26.4±3.3 | 19.8±2.8* | 18.3±1.6* |
|
| ||||
| SW, mmHg*μl | 3072±393.0 | 2963±693.3 | 3273±396.3 | 2415±819.0† |
|
| ||||
| CO, μl/min | 13108±1346.6 | 13537±1135.4 | 10947±1541.7* | 36.00±2.7*† |
|
| ||||
| EF, % | 71.82±3.0 | 69.12±4.8 | 79.83±6.8* | 9293±1465.8*† |
|
| ||||
| dP/dtmax, mmHg/s | 11075±2020.2 | 10722±2913.3 | 12079±2029.7 | 5595±955.3*† |
|
| ||||
| dP/dtmin mmHg/s | 9911±1287.4 | 9796±1834.5 | 10468±1025.0 | 4834±1487.7*† |
|
| ||||
| Tau, ms | 8.7±1.4 | 9.2±1.3 | 10.6±1.2 | 16.9±1.8*† |
Heart Rate (HR), end-systolic pressure (Pes), end-systolic volume (Ves), end-diastolic pressure (Ped), end-diastolic volume (Ved), Stroke Volume (SV), Stroke Work (SW), Cardiac Output (CO), Ejection Fraction (EF), the maximal rate of pressure increasing (+dP/dt), the maximal rate of pressure decreasing (−dP/dt), relaxation time constant calculated by the Glantz method (Tau).
*
p<0.05 vs. NTG Sham;
†
:p0.05 vs. NTG TAC.