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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Mol Cell Cardiol. 2015 May 22;85:104–116. doi: 10.1016/j.yjmcc.2015.05.012

Figure 7. Insulin signaling in hearts of 13 or 24 week-old UCP-DTA and control mice treated with saline or MnTBAP.

Figure 7

A, B. Western blots and densitometric analysis representing phosphorylation of Akt in 13 week-old UCP-DTA and control hearts perfused with or without 1nM insulin (n=4). C–E. Western blots and densitometric analysis representing phosphorylation of Akt and GSK3 in 24 week-old UCP-DTA and control hearts with or without 1nM insulin. E, F. Fold increase of insulin stimulated phospho-Akt and GSK3 over basal (n=5). *p<0.05 vs. other genotypes in the same groups; # p<0.05 for insulin- stimulated vs. basal state for same genotype.

Inline graphic Saline-treated control wildtype (WT) mice, Inline graphic MnTBAP-treated WT mice, Inline graphic UCP-DTA treated with saline, Inline graphic UCP-DTA treated with MnTBAP.