Table 4.

Cardiac dimensions and function measured in 24 week-old UCP-DTA (UD) mice by echocardiography.

	WT Saline	WT MnTBAP	UD Saline	UD MnTBAP
n	6	7	7	6
IVSd (cm)	0.092 ± 0.006	0.091 ± 0.004	0.111 ± 0.003 $	0.106 ± 0.002 $
IVSs (cm)	0.131 ± 0.006	0.131 ± 0.007	0.155 ± 0.003 $	0.144 ± 0.003
LVIDd (cm)	0.378 ± 0.007	0.377 ± 0.011	0.412 ± 0.010 $	0.400 ± 0.018
LVIDs (cm)	0.278 ± 0.008	0.270 ± 0.011	0.307 ± 0.010 $	0.289 ± 0.018
LVPWd (cm)	0.09 ± 0.005	0.084 ± 0.005	0.093 ± 0.006	0.090 ± 0.007
LVPWs (cm)	0.112 ± 0.006	0.102 ± 0.005	0.109 ± 0.007	0.105 ± 0.006
EF (%)	60.53 ± 1.43	63.23 ± 1.81	58.74 ± 1.36	62.20 ± 2.58
FS (%)	26.7 ± 0.9	28.48 ± 1.19	25.61 ± 0.82	27.87 ± 1.6
HR (beats/min)	531.5 ± 28.6	518.1 ± 17.37	544.19 ± 9.20	557.64 ± 18.55
SV (mL)	0.036 ± 0.001	0.035 ± 0.003	0.041 ± 0.003	0.039 ± 0.004

^$p<0.05 vs. WT saline and WT MnTBAP

IVSd, interventricular septum thickness in diastole; IVSs, interventricular septum thickness in systole; LVIDd, left-ventricular internal diameter in diastole; LVDs, left-ventricular internal diameter in systole; LVPWd, left-ventricular posterior wall thickness in diastole; LVPWs, left-ventricular posterior wall thickness in systole; EF, ejection fraction; FS, fractional shortening; HR, heart rate; SV, stroke volume