Skip to main content
. Author manuscript; available in PMC: 2016 Aug 15.
Published in final edited form as: J Immunol. 2015 Jul 15;195(4):1774–1781. doi: 10.4049/jimmunol.1500522

Figure 7. Summary of blood monocyte and DC differentiation in rhesus macaques.

Figure 7

Myeloid precursor cells in the bone marrow migrate into blood and give rise to CD14+CD16− classical monocytes. A large proportion of these classical monocytes rapidly disappeared from the circulation to become tissue macrophages. A fraction of the classical monocytes differentiated into CD14+CD16+ intermediate monocytes and then into CD14−CD16+ non-classical monocytes in the circulation. The populations of mDC, pDC and perhaps other unidentified DC appeared to differentiate from various DC precursors directly in the bone marrow prior entering the blood circulation.