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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2015 Mar 29;136(2):505–507. doi: 10.1016/j.jaci.2015.02.009

Table.

Association of CYP3A genetic polymorphisms and asthma control scores among 64 children receiving daily inhaled beclomethasone dipropionate.

Polymorphism Reference SNP (rs #) Association with Asthma Control Scores (P-value) ⊗ Reference Allele Frequency Variant Allele Frequency
CYP3A4
 CYP3A4*22 rs35599367 N/A 1.00 0.00
 CYP3A4 int 7 rs2246709 0.39 0.60 0.40
 CYP3A4 int 7 rs4646437 0.10 0.70 0.30
CYP3A5
 CYP3A5*3 rs776746 0.01 0.66 0.34
 CYP3A5*6 rs10264272 0.57 0.98 0.02
 CYP3A5*1D rs15524 0.01 0.66 0.34
CYP3A7
 CYP3A7 rs2687133 0.13 0.84 0.16
 CYP3A7*2 rs2257401 0.14 0.81 0.19
 CYP3A7 6 nt 5′ of ex 14 rs2740565 0.07 0.77 0.23
⊗

Bonferroni adjustment for multiple comparisons.

No patients identified with the variant allele (N/A).

All SNPs were in Hardy-Weinberg Equilibrium.