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. 2015 Aug;185(8):2259–2268. doi: 10.1016/j.ajpath.2015.04.015

Figure 4.

Figure 4

Immunohistochemistry of rat brain tissue. A and B: vascular endothelial growth factor (VEGF) expression using Alexa fluor 594 (red). Brain tissue without cyst (A) and brain tissue surrounded the cyst with high reactivity to anti-VEGF (B). C: Quantitative measurements of VEGF. D: IgG extravasation in rat brain tissue using anti-rat IgG peroxidase labeled. Brain tissue surrounding the cyst reveals reactivity to anti-rat IgG (brown). ∗∗∗∗P < 0.0001 between tissues surrounded the cyst and tissue without cyst. Original magnification: ×40 (A and B); ×2.5 (D).