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. 2015 Aug;185(8):2194–2205. doi: 10.1016/j.ajpath.2015.04.021

Figure 5.

Figure 5

Ablation of Wnt5a in liver epithelial cells has no effect on liver regeneration. A: Immunohistochemistry (IHC) for proliferating cell nuclear antigen (PCNA) shows comparable numbers of positive hepatocytes in the liver-specific knockouts of Wntless (Wls-LKO) and control (Con) at various time points after partial hepatectomy (PH). B: Quantification of PCNA staining shows insignificant differences in the number of positive hepatocytes in Con and Wls-LKO at various time points after PH. C: A Western blot analysis shows comparable levels of expression of cyclin-D1 at 40, 72, and 96 hours after PH in both Con and Wls-LKO. Original magnification, ×200 (A). GAPDH, glyceraldehyde-3-phosphate dehydrogenase.