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. 2015 Apr 30;22(8):628–635. doi: 10.1038/gt.2015.35

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Copyright © 2015 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Biodistribution and persistence of LEISHDNAVAX following single and multiple i.d. injections. Groups of 10 Wistar rats (5 male, 5 female) were injected once (a) or four times in weekly intervals (b–d) with 120 μg LEISHDNAVAX. Tissue samples were taken and processed 24 h (a and b), 14 days (c) or 60 days (d) after the last injection. Vector copy numbers were determined by qPCR. Single animal data and geometric mean values are given in log scale. Dotted lines indicate lower the limit of quantification LLOQ. Lnn ax: axillary lymph nodes; Lnn ing: inguinal lymph nodes; Lnn mes mesenteric lymph nodes; M. femoris: quadriceps muscle of thigh.