Table 3.
Odds ratios and 95% confidence intervals for the association between MUTYH gene haplotypes and RA.
| Haplotype | rs3219463 | rs3219476 | rs3219489 | rs3219493 | RA, % | Control, % | P value/cP value | Odds ratio (95% CI) |
|---|---|---|---|---|---|---|---|---|
| Ht1 | G | G | G | G | 150 (39.1) | 173 (45.1) | 0.0927/0.7416 | 0.78 (0.59–1.04) |
| Ht2 | A | T | C | G | 124 (32.3) | 102 (26.6) | 0.0815/0.652 | 1.32 (0.97–1.80) |
| Ht3 | G | T | C | G | 19 (4.9) | 11 (2.9) | 0.1362/1.0896 | 1.77 (0.83–3.76) |
| Ht4 | A | G | C | G | 17 (4.4) | 15 (3.9) | 0.718/5.744 | 1.14 (0.56–2.32) |
| Ht5 | G | T | G | G | 13 (3.4) | 12 (3.1) | 0.8389/6.7112 | 1.09 (0.49–2.41) |
| Ht6 | G | T | G | C | 13 (3.4) | 30 (7.8) | 0.0076*/0.0608 | 0.41 (0.21–0.81) |
| Ht7 | A | G | G | G | 11 (2.9) | 19 (4.9) | 0.1362/1.0896 | 0.57 (0.27–1.21) |
| Ht8 | G | G | C | G | 7 (1.8) | 21 (5.5) | 0.007*/0.056 | 0.32 (0.13–0.76) |
95% CI: 95% confidence intervals.
∗ P value of <0.05 was determined as statistically significant.
The chi-square test was performed to obtain the P value.
∗ cP value: P value corrected by Bonferroni correction.