Table 4.
Frequencies of rs3219463 genotypes of RA patients with various clinical features.
| rs3219463 genotype | RF | Extra-articular | Erosion | rs3219476 genotype | RF | Extra-articular | Erosion |
|---|---|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | ||
| G/− (n = 166) | 126 (75.9) | 81 (48.8) | 83 (50.0) | T/− (n = 165) | 119 (72.1) | 75 (45.5) | 87 (52.7) |
| A/A (n = 26) | 14 (53.8) | 10 (38.5) | 14 (53.8) | G/G (n = 27) | 22 (81.5) | 16 (59.3) | 10 (37.0) |
| P | 0.019* | 0.326 | 0.715 | P | 0.307 | 0.183 | 0.131 |
| OR | 2.700 | 1.525 | 0.857 | OR | 0.588 | 0.573 | 1.896 |
| 95% CI | 1.155–6.312 | 0.654–3.556 | 0.374–1.964 | 95% CI | 0.21–1.65 | 0.25–1.31 | 0.82–4.39 |
| A/− (n = 155) | 109 (70.3) | 76 (49.0) | 79 (51.0) | G/− (n = 159) | 120 (75.5) | 77 (48.4) | 77 (48.4) |
| G/G (n = 37) | 31 (83.8) | 15 (40.5) | 18 (48.6) | T/T (n = 33) | 21 (63.6) | 14 (42.4) | 20 (60.6) |
| P | 0.098 | 0.353 | 0.800 | P | 0.161 | 0.530 | 0.203 |
| OR | 0.459 | 1.411 | 1.097 | OR | 1.758 | 1.274 | 0.610 |
| 95% CI | 0.179–1.174 | 0.681–2.2922 | 0.535–2.249 | 95% CI | 0.79–3.90 | 0.60–2.72 | 0.28–1.31 |
95% CI: 95% confidence intervals. OR: odds ratio.
∗ P value of <0.05 was determined as statistically significant. The chi-square test was performed to obtain the P value.
RF: rheumatoid factors.