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. 2015 Jul 27;2015:380247. doi: 10.1155/2015/380247

Table 2.

Relationships between serum Mg with renal function and bone metabolism parameters in CKD patients with or without diabetes.

Dependent variables log⁡serum Mg (mg/dL) log⁡iPTH (pg/mL)
B β P 95% CI for B B β P 95% CI for B
With diabetes                
Renal function indicators†                
 log⁡eGFR (mL/min) −1.616 −0.473 0.014 (−2.869, −0.363) −0.191 −0.282 0.220 (−0.504, 0.122)
 log⁡creatinine (mg/dL) 1.539 0.528 0.007 (0.461, 2.616) 0.175 0.175 0.202 (−0.101, 0.451)
 log⁡BUN (mg/dL) 0.952 0.391 0.044 (0.026, 1.878) 0.027 0.056 0.810 (−0.202, 0.255)
Bone metabolism parameters‡                
 log⁡iPTH (pg/mL) 2.296 0.454 0.041 (0.109, 4.483)        
 log⁡Ca (mg/dL) −0.134 −0.546 0.015 (−0.239, −0.028) −0.030 −0.626 0.003 (−0.049, −0.012)
 log⁡P (mg/dL) 0.272 0.312 0.106 (−0.063, 0.608) 0.040 0.231 0.222 (−0.026, 0.106)
 log⁡ALP (U/L) 0.719 0.449 0.027 (0.093, 1.345) 0.168 0.529 0.005 (0.056, 0.279)
 log⁡25(OH)D (ng/mL) −0.369 −0.221 0.420 (−1.305, 0.567) −0.188 −0.570 0.023 (−0.348, −0.029)
 log⁡1,25(OH)2D (pg/mL) −0.286 −0.081 0.745 (−2.094, 1.523) −0.077 −0.110 0.649 (−0.422, 0.269)
Without diabetes                
Renal function indicators†                
 log⁡eGFR (mL/min) −1.091 −0.381 0.034 (−2.092, −0.090) 0.040 0.084 0.665 (−0.150, 0.231)
 log⁡creatinine (mg/dL) 0.922 0.404 0.040 (0.046, 1.798) −0.045 −0.119 0.577 (−0.210, 0.120)
 log⁡BUN (mg/dL) 0.426 0.172 0.368 (−0.531, 1.382) −0.020 −0.047 0.814 (0.814, 0.149)
Bone metabolism parameters‡                
 log⁡iPTH (pg/mL) 1.057 0.176 0.413 (−1.566, 3.679)        
 log⁡Ca (mg/dL) −0.153 −0.407 0.068 (−0.318, 0.012) 0.007 0.118 0.597 (−0.021, 0.026)
 log⁡P (mg/dL) 0.148 −0.135 0.508 (−0.605, 0.308) −0.065 −0.355 0.065 (−0.134, −0.004)
 log⁡ALP (U/L) 0.221 0.155 0.469 (−0.400, 0.841) 0.085 0.357 0.078 (−0.010, 0.179)
 log⁡25(OH)D (ng/mL) −1.250 −0.580 0.002 (−1.993, −0.507) −0.079 −0.219 0.273 (−0.223, 0.066)
 log⁡1,25(OH)2D (pg/mL) 0.895 0.255 0.245 (−0.656, 2.446) 0.107 0.183 0.392 (−0.147, 0.362)

(1) eGFR, estimated glomerular filtration rate; BUN, blood urine nitrogen; iPTH, intact parathyroid hormone; ALP, alkaline phosphatase; 25(OH)D, 25-hydroxyvitamin D; 1,25(OH)2D, 1,25-dihydroxyvitamin D.

(2) All outcomes of the multiple regression analysis are presented in unstandardized coefficients (B) and standardized coefficients (β) and at a 95% confidence interval (CI) for B. A P value less than 0.05 was considered statistically significant. †Adjusted gender and age. ‡Adjusted gender, age, albumin, and eGFR.