Table 3.
GDF-15 patents related to diabetes, cardiovascular diseases, and chronic kidney diseases.
| Patent | Applicant | Title |
|---|---|---|
| WO2011144571A2 | F. Hoffmann-La Roche Ag | GDF-15 based means and methods for survival and recovery prediction in acute inflammation |
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| WO2012138919A2 | Amgen Inc. | Method of treating or ameliorating metabolic disorders using GDF-15 |
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| WO2012146645A1 | F. Hoffmann-La Roche Ag | Diagnosis of kidney injury after surgery |
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| EP2336784A1 | Roche Diagnostics GmbH | GDF-15 and/or Troponin T for predicting kidney failure in heart surgery patients |
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| ||
| EP2388594A1 | Roche Diagnostics GmbH | GDF-15 based means and methods for survival and recovery prediction in acute inflammation |
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| WO2009141357A1 | Roche Diagnostics Gmbh, F. Hoffmann-La Roche Ag | GDF-15 as biomarker in type 1 diabetes |
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| US 8,771,961 B2 | Roche Diagnostics Operations, Inc. | Monitoring myocardial infarction and its treatment |
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| EP1884777A1 | Medizinische Hochschule Hannover | Means and methods for assessing the risk of cardiac interventions based on GDF-15 |
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| EP2439535A1 | F. Hoffmann-La Roche AG | Diagnosis of diabetes related heart disease, GDF-15 and Troponin as predictors for the development of type 2 diabetes mellitus |
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| WO2013113008A1 | Amgen Inc. | GDF-15 polypeptides-ameliorating metabolic disorders |
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| WO2010048670A1 | St. Vincent's Hospital Sydney Limited | Method of prognosis in chronic kidney disease |
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| WO2011073382A1 | Roche Diagnostics Gmbh | GDF-15 and/or troponin T for predicting kidney failure in heart surgery patients |