Table 3.
Genotype and allele frequency distribution of rs10885409 of TCF7L2 and PPAR-γ P12A mutation without obesity consideration.
| Total N | T2DM patients N (%) |
Nondiabetic subjects N (%) |
P value | |
|---|---|---|---|---|
| TCF7L2 genotypes | ||||
| TT | 111 | 61 (22.5) | 50 (23.3) | NS |
| CT | 221 | 121 (44.6) | 100 (46.5) | NS |
| CC | 154 | 89 (32.9) | 65 (30.2) | NS |
| Allele frequencies | ||||
| T | 443 | 243 (0.45) | 205 (0.48) | NS |
| C | 529 | 299 (0.55) | 225 (0.52) | NS |
| PPAR-γ genotypes | ||||
| CC | 447 | 250 (91.9) | 197 (91.2) | NS |
| CG | 41 | 22 (8.1) | 19 (8.8) | NS |
| GG | 0 | 0 | 0 | NS |
| Allele frequencies | ||||
| C | 935 | 522 (0.96) | 413 (0.96) | NS |
| G | 41 | 22 (0.04) | 19 (0.04) | NS |