Table 2.
Association between IR and sex, obesity, sarcopenia, low adiponectin, life-style habits, and HFDM2 in adolescents (n = 667).
| Subjects with insulin resistance (HOMA-IR ≥ 2.6) | Crude ORa | ||
|---|---|---|---|
| n | % | ||
| Overall | 109 | 16.32 | |
| Obesity | |||
| No | 65 | 11.4 | Ref. group |
| Yes | 44 | 45.8 | 6.60 [4.09–10.6]*** |
| Sarcopenia | |||
| No | 50 | 10.8 | Ref. group |
| Yes | 59 | 35.1 | 4.87 [3.17–7.50]*** |
| Low adiponectin | |||
| No | 74 | 13.6 | Ref. group |
| Yes | 35 | 28.5 | 2.53 [1.59–4.01]*** |
| Physical inactivity | |||
| No | 53 | 13.2 | Ref. group |
| Yes | 56 | 21.1 | 1.77 [1.17–2.67]*** |
| Unhealthy food intake | |||
| No | 89 | 17.5 | Ref. group |
| Yes | 20 | 12.6 | 0.68 [0.40–1.14]*** |
| Family history T2Db | |||
| No | 23 | 11.7 | Ref. group |
| Yes | 74 | 18.8 | 1.73 [1.10–2.88]*** |
aStatistical significance: * P < 0.05, ** P < 0.01, and *** P < 0.001; obesity: BMI z-score ≥2 SD; sarcopenia: % FFMI ≤25th percentile; low adiponectin: adiponectin ≤7.9 μg/mL; physical inactivity: PA score ≤3; unhealthy food intake: eating test score ≤4.4; FHDMb:family history of type 2 diabetes in at least one first-degree relative (n = 590).