Table 1.
Clinical characteristics of study subjects.
| Non-PCOS without IR (n = 7) |
Non-PCOS with IR (n = 9) |
PCOS (n = 8) |
PCOS with IR (n = 11) |
|
|---|---|---|---|---|
| BMI (kg/m2) | 24.58 ± 5.47 | 34.97 ± 6.76∗∗ | 24.81 ± 3.16 | 31.31 ± 5.55 |
| Age (yrs) | 33.17 ± 8.47 | 34.86 ± 7.08 | 28.29 ± 2.36 | 27.00 ± 4.76 |
| mFG score | 0.17 ± 0.41 | 0.63 ± 0.92 | 5.71 ± 5.40∗ | 7.00 ± 3.59∗∗ |
| Free testosterone (pg/mL) | 1.73 ± 0.33 | 2.66 ± 1.29 | 4.56 ± 2.47∗ | 6.66 ± 2.51∗∗ |
| Total testosterone (ng/mL) | 26.50 ± 5.54 | 23.86 ± 3.76 | 45.71 ± 25.42 | 37.90 ± 19.14 |
| DHEAS (µg/dL) | 127.8 ± 30.7 | 252.7 ± 31.7∗ | 286.3 ± 31.2∗∗ | 244.6 ± 23.1∗ |
| Fasting glucose (mcg/dL) | 68.50 ± 14.39 | 87.38 ± 8.85 | 88.14 ± 5.58∗ | 93.15 ± 17.03∗∗ |
| Fasting insulin (mIU/mL) | 5.00 ± 3.56 | 13.75 ± 3.24∗ | 5.50 ± 2.35 | 20.43 ± 7.16∗∗++ |
| HOMA-IR | 0.88 ± 0.67 | 2.94 ± 0.66∗ | 1.20 ± 0.58 | 4.65 ± 1.61∗∗++ |
| Prolactin (ng/mL) | 13.3 ± 5.50 | 10.99 ± 5.54 | 10.37 ± 5.14 | 12.83 ± 5.99 |
| TSH (IU/mL) | 2.05 ± 0.53 | 2.94 ± 1.48 | 1.66 ± 0.70 | 1.95 ± 0.93 |
| 17-HP (ng/dL) | 25.29 ± 9.23 | 21.14 ± 7.24 | 29.90 ± 20.09 | 35.86 ± 14.86 |
Data are expressed as mean ± SD.
∗∗ P < 0.01 versus control group.
∗ P < 0.05 versus control group.
++ P < 0.01 versus PCOS group.
mFG score is the modified Ferriman-Gallwey hirsutism score; HOMA-IR is homeostasis model assessment for estimating insulin resistance. DHEAS is dehydroepiandrosterone sulfate, TSH is thyroid stimulating hormone, and 17-HP is 17 alpha-hydroxyprogesterone.