Table 2.
Inflammatory profile in total T1D population and in patients with and without MS.
| Parameter | T1D population (n = 140) |
Patients with MS (n = 61) |
Patients without MS (n = 79) |
p * |
|---|---|---|---|---|
| IL-8, pg/mL (median, IR) | 18.2 (8.68–41.22) |
24.6 (12.65–46.5) |
13.4 (7.0–34.4) |
0.064 |
| IL-6, pg/mL (median, IR) | 1.5 (1.5–3.2) |
1.5 (1.5–4.7) |
1.5 | NS |
| IL-10, pg/mL (median, IR) | 2.3 (2.3–3) |
2.3 (2.3–4.4) |
2.3 | NS |
| TNF, pg/mL (median, IR) | 2.7 (2.7–4.8) |
2.7 (2.7–7.8) |
2.7 | NS |
| Adiponectin, pg/mL (median, IR) | 9.4 (5.7–15.5) |
8.9 (5.4–14.9) |
9.4 (6.6–15.6) |
NS |
| Resistin, pg/mL (median, IR) |
1180.3 (775.8–1896.8) |
1627.4 (838.8–2233.8) |
1055 (631.8–1459.2) |
0.010 |
| %Patients with resistin >1108 pg/mL | 55% | 71% | 44% | 0.021 |
IR: interquartile range, T1D: type 1 diabetes, MS: metabolic syndrome, NS: not significant, IL-8: interleukin-8, IL-6: interleukin-6, IL-10: interleukin-10, and TNF: tumor necrosis factor. *Comparing patients with and without MS, using Mann-Whitney U test.