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. 2015 Jul 27;2015:819232. doi: 10.1155/2015/819232

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Copyright © 2015 Yi Tian et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Isoflurane (Iso) and captopril (Cap) ameliorated postischemic myocardial oxidative stress in rabbits. (a) Cardiac malondialdehyde (MDA) content, (b) plasma superoxide dismutases (SOD) levels. Sham: sham operated control; I/R: rabbits subjected to myocardial ischemia reperfusion (MI/R); Cap: rabbits treated with captopril (25 mg/kg given intravenously 24 h) prior to inducing MI/R; Iso: rabbits received isoflurane preconditioning (15 min 1.1% end tidal isoflurane followed by a 15 min washout period before inducing MI/R); Iso+Cap: rabbits received captopril in combination with Iso. Data are shown as means ± SD, with n = 8 animals per group. ^# P < 0.05 versus Sham, ^* P < 0.05 versus I/R, and ^& P < 0.05 versus IPC.