Table 1.
Baseline characteristics of the study population.
| Item | Control | Cap1hr | Cap3d | Cap1hr+Iso | Cap3d+Iso |
|---|---|---|---|---|---|
| Gender (male/female) | 14/6 | 14/6 | 15/5 | 13/7 | 14/6 |
| Age (years) | 46.2 ± 5.9 | 46.8 ± 7.5 | 44.5 ± 6.9 | 43.2 ± 7.2 | 45.3 ± 6.1 |
| Body weight (Kg) | 58.2 ± 7.2 | 61.7 ± 8.1 | 62.1 ± 9.0 | 61.2 ± 7.9 | 59.7 ± 8.3 |
| LVEF (%) | 55.2 ± 6.9 | 55.3 ± 6.9 | 53.1 ± 7.8 | 54.2 ± 7.4 | 56.6 ± 6.3 |
| Premedication | |||||
| Digoxin (n) | 6 | 6 | 7 | 5 | 6 |
| Diuretic (n) | 8 | 7 | 6 | 7 | 8 |
Control: untreated control; Cap1hr: captopril treatment for 1 h before surgery (12.5 mg, p.o., 1 h before surgery); Cap3d: captopril treatment for 3 days (12.5 mg, p.o., 3 times a day) before surgery; Cap1hr+Iso: captopril treatment for 1 h in combination with inhalational isoflurane (Iso) at 1.1% end tidal concentration administrated for 30 min before CPB; Cap3d+Iso: captopril treatment for 3 days in combination with Iso before CPB. Values are means ± S.D. or the number of patients. No significant differences were observed among groups; LVEF: left ventricular ejection fraction.