TABLE 3.
Differential Improvements Over Time in Death-Censored Graft Survival and Patient Survival Across Various Subgroups of Pediatric (<18 years old) Kidney Transplant Recipients Between 1987 and 2012 (n = 17 446)
| DCGS | ||
|---|---|---|
| aHR (95% CI) | P | |
| All patients | 0.95 (0.94–0.96) | <.001 |
| Recipient age | ||
| 0–2 years | 0.94 (0.92–0.96) | <.001 |
| 3–5 years | 0.93 (0.91–0.95) | <.001 |
| 6–12 years | 0.94 (0.93–0.95) | <.001 |
| 13–17 years | 0.96 (0.95–0.96) | <.001 |
| Recipient gender | ||
| Female | 0.96 (0.95–0.97) | <.001 |
| Male | 0.94 (0.93–0.95) | <.001 |
| Dialysis history | ||
| Preemptive | 0.94 (0.92–0.95) | <.001 |
| Pretransplant dialysis | 0.95 (0.95–0.96) | <.001 |
| Etiology of renal disease | ||
| FSGS | 0.97 (0.95–0.98) | <.001 |
| Other glomerular | 0.95 (0.94–0.96) | <.001 |
| CAKUT | 0.94 (0.93–0.95) | <.001 |
| Other/missing | 0.95 (0.94–0.96) | <.001 |
| Patient Survival | ||
| aHR (95% CI) | P | |
| All patients | 0.95 (0.94–0.97) | <.001 |
| Peak PRA | ||
| 0%–20% | 0.96 (0.95–0.97) | <.001 |
| 21%–80% | 0.96 (0.93–0.98) | .002 |
| 81%–100% | 0.90 (0.86–0.94) | <.001 |
CAKUT, congenital anomalies of the kidney and urinary tract; IQR, interquartile range.