TABLE 3.
Differential Improvements Over Time in Death-Censored Graft Survival and Patient Survival Across Various Subgroups of Pediatric (<18 years old) Kidney Transplant Recipients Between 1987 and 2012 (n = 17 446)
DCGS | ||
---|---|---|
aHR (95% CI) | P | |
All patients | 0.95 (0.94–0.96) | <.001 |
Recipient age | ||
0–2 years | 0.94 (0.92–0.96) | <.001 |
3–5 years | 0.93 (0.91–0.95) | <.001 |
6–12 years | 0.94 (0.93–0.95) | <.001 |
13–17 years | 0.96 (0.95–0.96) | <.001 |
Recipient gender | ||
Female | 0.96 (0.95–0.97) | <.001 |
Male | 0.94 (0.93–0.95) | <.001 |
Dialysis history | ||
Preemptive | 0.94 (0.92–0.95) | <.001 |
Pretransplant dialysis | 0.95 (0.95–0.96) | <.001 |
Etiology of renal disease | ||
FSGS | 0.97 (0.95–0.98) | <.001 |
Other glomerular | 0.95 (0.94–0.96) | <.001 |
CAKUT | 0.94 (0.93–0.95) | <.001 |
Other/missing | 0.95 (0.94–0.96) | <.001 |
Patient Survival | ||
aHR (95% CI) | P | |
All patients | 0.95 (0.94–0.97) | <.001 |
Peak PRA | ||
0%–20% | 0.96 (0.95–0.97) | <.001 |
21%–80% | 0.96 (0.93–0.98) | .002 |
81%–100% | 0.90 (0.86–0.94) | <.001 |
CAKUT, congenital anomalies of the kidney and urinary tract; IQR, interquartile range.