Table 3.
miRNA name | Accessiona | FCb | p-Valuec | Gene name | RefSeq | FCd | p-Valuec | Correlatione miRNA:mRNA (r; p) | Correlationf miRNA:Ki-67% (r; p) | Correlationf miRNA:P53% (r; p) |
---|---|---|---|---|---|---|---|---|---|---|
miR-183 | MI0000273 | −2.74 | 0.018 | KIAA0101 | NM_014736.4 | 3.071 | 0.0002 | −0.87; 0.0001 | −0.58; 0.002 | −0.59; 0.0014 |
miR-340* | MI0000802 | −1.86 | 0.015 | NEK2 | NM_002497.2 | 16.340 | 0.0077 | −0.53; 0.0475 | −0.24; ns | −0.19; ns |
miR-98 | MI0000100 | −1.92 | 0.028 | AURKB | NM_004217.2 | 5.022 | 0.0002 | −0.75; 0.0042 | −0.38; 0.0263 | −0.19; ns |
CCNB2 | NM_004701.2 | 2.278 | 0.0084 | −0.76; 0.0032 | ||||||
CENPK | NM_022145.3 | 2.468 | 0.0009 | −0.89; 0.0001 | ||||||
UBE2T | NM_014176.3 | 3.810 | 0.0236 | −0.53; 0.0478 | ||||||
E2F2 | NM_177733.6 | 3.043 | 0.0076 | −0.56; 0.0340 | ||||||
miR-744 | MI0005559 | −1.93 | 0.015 | TGFB1 | NM_000660.4 | 2.640 | 0.0079 | −0.55; 0.0408 | −0.31; ns | −0.31; ns |
In miRNA name * stands for “minor miRNA” meaning the miRNA originating for the preferentially degraded strand.
aAccession number from Mirbase.
bFC, fold change of miRNA expression in A tumors compared to NA tumors (26 tumors).
cp-Value from Student’s test comparing A vs. NA tumors.
dFold change of gene expression in A vs. NA tumors (26 tumors).
eCorrelation coefficient calculated between miRNA expression and their target gene (miRNA:mRNA) using Pearson test. Coefficient (r) and p-value (p) are given in that for each couple.
fCorrelation coefficient calculated between miRNA expression and Ki-67% (miRNA:Ki67%) or P53% (miRNA:P53%) using Spearman test. Coefficient (r) and p-value (p) are given in that for each couple.