Table 3.

Predicted target of deregulated miRNA with inverse correlation in expression level.

miRNA name	Accessiona	FCb	p-Valuec	Gene name	RefSeq	FCd	p-Valuec	Correlatione miRNA:mRNA (r; p)	Correlationf miRNA:Ki-67% (r; p)	Correlationf miRNA:P53% (r; p)
miR-183	MI0000273	−2.74	0.018	KIAA0101	NM_014736.4	3.071	0.0002	−0.87; 0.0001	−0.58; 0.002	−0.59; 0.0014
miR-340*	MI0000802	−1.86	0.015	NEK2	NM_002497.2	16.340	0.0077	−0.53; 0.0475	−0.24; ns	−0.19; ns
miR-98	MI0000100	−1.92	0.028	AURKB	NM_004217.2	5.022	0.0002	−0.75; 0.0042	−0.38; 0.0263	−0.19; ns
				CCNB2	NM_004701.2	2.278	0.0084	−0.76; 0.0032
				CENPK	NM_022145.3	2.468	0.0009	−0.89; 0.0001
				UBE2T	NM_014176.3	3.810	0.0236	−0.53; 0.0478
				E2F2	NM_177733.6	3.043	0.0076	−0.56; 0.0340
miR-744	MI0005559	−1.93	0.015	TGFB1	NM_000660.4	2.640	0.0079	−0.55; 0.0408	−0.31; ns	−0.31; ns

In miRNA name * stands for “minor miRNA” meaning the miRNA originating for the preferentially degraded strand.

^aAccession number from Mirbase.

^bFC, fold change of miRNA expression in A tumors compared to NA tumors (26 tumors).

^cp-Value from Student’s test comparing A vs. NA tumors.

^dFold change of gene expression in A vs. NA tumors (26 tumors).

^eCorrelation coefficient calculated between miRNA expression and their target gene (miRNA:mRNA) using Pearson test. Coefficient (r) and p-value (p) are given in that for each couple.

^fCorrelation coefficient calculated between miRNA expression and Ki-67% (miRNA:Ki67%) or P53% (miRNA:P53%) using Spearman test. Coefficient (r) and p-value (p) are given in that for each couple.