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. 2015 Aug 10;5:13170. doi: 10.1038/srep13170

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Copyright © 2015, Macmillan Publishers Limited

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(a) Decreased miR-378a-3p expression levels in breast cancer tissues compared with those in paired adjacent normal tissues. miR-378a-3p expression levels were determined by qPCR and normalized to RNU48 levels. **P < 0.01. (b) Kaplan-Meier survival analysis according to miR-378a-3p levels in tamoxifen-treated breast cancer patients. The recurrence free survival of miR-378a-3p high-expressing group (n = 74) was significantly lower than that of the low-expressing group (n = 35; log-rank test; P = 0.012).