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Representative islets in pancreas from donor H0015 immunostained for glucagon (brown) showed great variability in islet composition, both in the proportion of cell types and the clarity of β-cell core arrangement. The smaller islets resemble those of rodents with a clear mantle-core pattern. However, as shown here, even the larger islets with fewer β-cells have a discernible clustering of β-cells. Scale, 50 µm.
