Table 2.
Cell Composition of Human Islets in Islets of Different Sizes.
| More Than 100 |
30–99 |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Donor | Age(Years) | Sex | BMI | Counted Cells | Islets | Cells/Islet | β-Cells (%) | Cells/islet | β-Cells (%) |
| H0015 | 15 | M | 25.1 | 2402 | 23 | 225 | 45.5 | 51.5 | 74.1 |
| H0017 | 23 | M | 26.0 | 3354 | 35 | 159 | 65.5 | 62.8 | 76.6 |
| H0018 | 48 | F | 17.9 | 3137 | 30 | 161 | 56.1 | 66.7 | 72.3 |
| H0019 | 64 | F | 20.8 | 4146 | 36 | 189 | 64.2 | 56.0 | 68.2 |
| H0020 | 16 | M | 32.5 | 2624 | 27 | 164 | 59.7 | 51.4 | 70.2 |
| H0021 | 39 | F | 22.5 | 3108 | 34 | 154 | 60.6 | 57.1 | 77.4 |
| H0022 | 53 | F | 23.5 | 3537 | 35 | 186 | 67.7 | 56.9 | 80.6 |
| Mean ± SEM | 31.4 ± 1.9 | 176.9 ± 9.5 | 59.9 ± 2.8* | 57.5 ± 2.1 | 74.2 ± 1.6* | ||||
*
Two-tailed unpaired t-test; significance; p<0.0019. BMI, body mass index; M, male; F, female; 30–99 cells represents islets that are 60–175 µm in diameter; 100+ cells represents islets that are <175 µm in diameter.