Figure 7.

Summary Data. (A) Overall percentages of MHC-I immunoreactive islets (elevated and hyper-expressing islets) are represented as a heat map. Areas with higher (red) or lower (green) presence of affected islets are shown for all of the sections. (B) Overall mean numbers of CD8 T cells per islet section (elevated, hyper-expressing and normal) are represented as a heat map. Areas that contained islets with higher (red) or lower (green) numbers of infiltrating CD8 T cells are shown for all sections together. (C) Correlation analysis of the percentages of MHC-I immunoreactive islets and the number of CD8 T cells per islet section (r = 0.61). ****p≤0.0001. Scale, 1000 µm.