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. 2015 Aug 10;5:11754. doi: 10.1038/srep11754

Figure 7. STIM1 in DU145 cells compromise tumor growth with acceleration of the EMT and increased cell senescence in tumor xenografts in vivo.

Figure 7

A. Tumor growth curves in NOD/SCID mice inoculated with DU145-YFP (n = 5), DU145-STIM1-YFP (n = 6), DU145-ORAI1 (n = 4), and DU145-ORAI1-STIM1-YFP (n = 4). B. Immunofluorescent image of BrdU in tumor xenograft tissues; the images represent one of 4–6 mice from each group. C. Statistical analysis of BrdU-positive cell percentage from tumor xenograft tissues in each image field. D. Immunohistochemical staining of STIM1, ORAI1, DcR2 and Vimentin (all in brown) and immunofluorescence staining of E-cadherin (red) in different tumor xenograft tissues.