Table 5. Risk analysis for early mortality in patients <2.5kg.
| Univariate risk analysis for early mortality on patients <2.5kg | |||
|---|---|---|---|
|
| |||
| survivors (n=130) | early deaths (n=16) | p-value | |
|
| |||
| gestational age (continuous variable) (mean±DS)(weeks) | 35.7±2.8 | 34±2.7 | 0.013* |
|
| |||
| gestational age <36 weeks | 50 (38.5%) | 11 (68.8%) | 0.03* |
|
| |||
| prematurity (gestational age <37 weeks) | 70 (53.8%) | 12 (75%) | 0.12 |
|
| |||
| Birthweight | 2.13±0.43 kg | 2.02±0.44 kg | 0.22 |
| AGA: 71 (54.6%) | AGA: 10 (62.5%) | 0.26 | |
| SGA: 57 (43.8%) | SGA: 5 (31.3%) | ||
| LGA: 2 (1.5%) | LGA: 1 (6.3%) | ||
|
| |||
| Antenatal diagnosis | 84 (64.6%) | 11 (68.8%) | 1.00 |
|
| |||
| Major extracardiac malformation | 25 (19.2%) | 2 (12.5%) | 0.73 |
|
| |||
| genetic syndrome | 17 (13.1%) | 3 (18.8%) | 0.46 |
|
| |||
| Surgeon | surgeon 1: 19(14.6%) | surgeon 1: 2 (12.5%) | 0.072 |
| surgeon 2: 53 (40.8%) | surgeon 2: 2 (12.5%) | ||
| surgeon 3: 25 (19.2%) | surgeon 3: 4 (25%) | ||
| surgeon 4: 33 (25.4%) | surgeon 4: 8 (50%) | ||
|
| |||
| Age at surgery (days) (median, range) | 7 (1; 91) | 12.5 (1;64) | 0.25 |
|
| |||
| Weight at surgery | 2.22±0.25 | 2.12±0.35 | 0.26 |
|
| |||
| STAT score (mean) | 3.61±1.1 | 3.69±0.94 | 0.89 |
|
| |||
| Pathway: | - Univentricular: 36 (27.7%) | - Univentricular: 5 (31.3%) | 0.77 |
| - Palliation towards biventricular: 11 (8.5%) | - Palliation towards biventricular: 2 (12.5%) | ||
| - Biventricular: 83 (63.8%) | - Biventricular: 9 (56.3%) | ||
|
| |||
| Timing of surgery | - Usual: 108 (83.1%) | - Usual: 11 (68.8%) | 0.17 |
| - Delayed: 22 (16.9%) | - Delayed: 5 (31.3%) | 0.30 | |
|
| |||
| Bypass | 122 (93.8%) | 16 (100%) | 0.30 |
|
| |||
| Bypass time | 110±50 | 102±48 | 0.67 |
|
| |||
| Postoperative complications | 41 (31%) | 16 (100%) | <0.0001* |
|
| |||
| delayed chest closure | 15 (11.5%) | 5 (31.3%) | 0.047* |
|
| |||
| cardiac arrest | 4(3.1%) | 14 (87.5%) | <0.0001* |
|
| |||
| length of mechanical ventilation (median) (days) | 4 (1; 32) | 12 (1;41) | 0.09 |
|
| |||
| Arrhythmia | 11 (8.5%) | 7 (43.8%) | 0.001* |
|
| |||
| AV block requiring pacemaker | 1 (0.8%) | 2 (12.5%) | 0.03* |
|
| |||
| Pulmonary complications | 17 (13.1%) | 6 (37.5%) | 0.02* |
|
| |||
| Renal failure requiring dialysis | 0 | 1 (6.3%) | 0.004* |
|
| |||
| Necrotizing entrocolitis | 6 (4.6%) | 2 (12.5%) | 0.21 |
|
| |||
| Early unplanned reintervention | 7 (5.4%) | 2 (12.5%) | 0.25 |
|
| |||
| Residual lesions at discharge | 32 (24.6%) | 6 (37.5%) | 0.36 |
|
| |||
| Multivariate analysis | |||
|
| |||
| p-value | OR | 95% confidence interval | |
|
| |||
| gestational age (continuous variable, in weeks) | 0.037 | 0.83 | 0.69-0.98 |
Factors of adjustment for the multivariate analysis: surgeon, STAT score, type of procedure (uni/biventricular), gestational age at birth.