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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Periodontol 2000. 2015 Oct;69(1):201–220. doi: 10.1111/prd.12095

Fig. 2. Concurrent miRNA and mRNA profiling of human gingival tissues.

Fig. 2

The largest study of miRNA expression in human periodontitis lesions available to date (Stoecklin-Wasmer et al. [156]) reported data from 86 systemically healthy, non-smoking subjects with moderate to severe periodontitis. Genome-wide miRNA and mRNA profiling was concurrently carried out in 198 gingival tissue samples, 40 of which were harvested from periodontally ‘healthy’ sites and 158 from ‘diseased’ sites. miRNA and mRNA expression data where analyzed to distinguish between predicted and actual gene targets.