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. Author manuscript; available in PMC: 2015 Aug 19.
Published in final edited form as: Nature. 2015 Feb 19;518(7539):365–369. doi: 10.1038/nature14252

Extended Data Figure 8. Enrichment of tissue-specific enhancer annotations from the Roadmap Epigenomics Consortium for AD-associated SNPs and mouse enhancers.

Extended Data Figure 8

Enrichment of AD-associated SNPs (y-axis, permutation P value) in tissue-specific enhancer annotations from the Roadmap Epigenomics Consortium (points), relative to their enrichment for a, increased-level and b, decreased-level (colors of different classes along y-axis) of orthologous enhancer regions in the mouse AD model (x-axis, hypergeometric P value). Linear regression trend line and R2, based on Pearson correlation is shown.