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. Author manuscript; available in PMC: 2015 Aug 19.
Published in final edited form as: Nature. 2015 Feb 19;518(7539):365–369. doi: 10.1038/nature14252

Extended Data Figure 1. Epigenomic and transcriptomic profiling of a mouse model of AD.

Extended Data Figure 1

a, Experimental design and progression pathology in the CK-p25 mice. b, Gene expression and histone modification levels at the SPI1 locus at 6 weeks of inducible p25 overexpression. Profiled are histone marks associated with repression (blue); histone marks associated with enhancers (orange); histone marks associated with promoters (red); histone marks associated with gene bodies (green); RNA-seq (black).