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. Author manuscript; available in PMC: 2015 Aug 10.
Published in final edited form as: J Hepatol. 2014 Aug 23;62(2):325–331. doi: 10.1016/j.jhep.2014.08.024

Figure 1.

Figure 1

Figure 1

1a: top panel- Hepatic DDAH-1 is located within the cytoplasm of hepatocytes of human liver; DDAH-1 levels are markedly decreased in cirrhotic liver (right side image) compared to a healthy liver (left side image).

Similarly, in the BDL rat model of cirrhosis, DDAH-1 is predominantly located in the hepatocyte cell fraction from rat liver as compared with the non-hepatocyte cell (NPC) fraction (1b: left panel), and DDAH-1 protein levels are markedly reduced in BDL rat liver compared to sham (1c: centre panel). By contrast, hepatic DDAH-2 protein levels are increased in BDL rat liver compared to sham (1d: right panel).