Table 2.
Top GeneGo process networks represented by FMR4-responsive genes identified by microarray analysis.
| Category | GeneGo process networks | p-value |
|---|---|---|
| Apoptosis | Death domain receptors and caspases in apoptosis | 0.02682 |
| Cell adhesion | Platelet aggregation | 0.02999 |
| Leucocyte chemotaxis | 0.04076 | |
| Cell cycle | G1/S Interleukin regulation | 0.00000 |
| G1-S Growth factor regulation | 0.00002 | |
| Cytoskeleton | Actin filaments | 0.00022 |
| Actin filaments | 0.03088 | |
| Development | Hemopoiesis, erythropoietin pathway | 0.00000 |
| Neurogenesis and synaptogenesis | 0.08499 | |
| Neuromuscular junction | 0.11290 | |
| Wnt/beta-catenin, notch, VEGF, IP3, and integrin signaling | 0.11674 | |
| DNA Damage | Checkpoint | 0.00006 |
| Immune response | BCR pathway | 0.00008 |
| Inflammation | MIF signaling | 0.00000 |
| IL-2 signaling | 0.00003 | |
| Protein C signaling | 0.06668 | |
| Kallikrein–kinin system | 0.09179 | |
| Reproduction | FSH-beta signaling pathway | 0.00001 |
| Signal | CREM pathway | 0.00002 |
| Transduction | Neuropeptide signaling pathways | 0.01407 |