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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Eur J Immunol. 2015 May 6;45(7):2052–2060. doi: 10.1002/eji.201445324

Table 1.

3DL2*001 and the SNP 1190T are associated to pemphigus foliaceus

Patients Controls
P A F (%) P A F(%) p OR 95% CI
Allele frequencies
001 Euro 46 160 22.3 22 156 12.4 0.007 2.04 1.17 – 3.54
Afro 29 75 27.9 18 81 18.2 0.070 1.74 0.89 – 3.39
Total 75 235 24.2 40 237 14.4 0.002 1.89 1.24 – 2.89

Carrier frequencies
001 Euro 39 65 37.5 20 70 22.2 0.015 2.10 1.11 – 3.97
Afro 24 28 46.2 17 34 33.3 0.129 1.71 0.77 – 3.81
Total 63 93 40.4 37 104 26.2 0.010 1.90 1.16 – 3.11

Genotypes
001/001 Total 12 144 7.7 3 138 2.1 0.025 3.83 1.06 – 13.87
001/other Total 51 105 32.7 34 107 24.1 0.087 1.55 0.93 – 2.60

SNPs
322A Euro 40 64 38.5 45 45 50.0 0.071 0.63 0.35 – 1.11
Afro 27 25 51.9 24 27 47.1 0.308 0.70 0.35 – 1.38

337G Euro 29 75 27.9 24 66 26.7 0.490 1.06 0.56 – 2.00
Afro 9 43 17.3 15 36 29.4 0.146 0.50 0.20 – 1.28

1190T Euro 40 64 38.5 49 44 54.4 0.018 0.52 0.29 – 0.93
Afro 23 29 44.2 21 30 41.2 0.752 1.13 0.52 – 2.47

P=presence; A=absent; F=frequency, p=p-value; OR=odds ratio, CI=confidence interval. For simplification, KIR3DL2*001 is represented as 001. Bold highlights the significant associations.