Table 1.
Results of laboratory studies obtained at patient presentation
| Laboratory test | Case 1 | Case 2 |
|---|---|---|
| Whole blood, serum, or plasma | ||
| White blood cell count, 103 cells/μL | 7.3 | 9.5 |
| Hemoglobin, g/dL | 13.7 | 15.4 |
| Platelet count, 103 cells/μL | 238 | 115 |
| Creatinine, mg/dL | 1.0 | 2.3 |
| Glucose, mg/dL | 127 | 112 |
| Bilirubin, total, mg/dL | 0.5 | 2.2 |
| Alkaline phosphatase, units/L | 88 | 153 |
| Aspartate transaminase, units/L | 38 | 61 |
| Alanine transaminase, units/L | 52 | 136 |
| Blood culture | No growth | No growth |
| Malaria peripheral smear and BinaxNOW | Negative | Negative |
| Human immunodeficiency virus | ||
| Fourth-generation screen | Not tested | Negative |
| Quantitative RT-PCR | Not detected | Not detected |
| West Nile virus IgM | Negative | Not tested |
| Real-time RT-PCR for dengue, yellow fever, chikungunya, Zika, West Nile, and Japanese encephalitis viruses | Not detected | Not detected |
| CSF | ||
| Description | Clear | Clear |
| White blood cell count, cells/μL | 75 | 1* |
| Neutrophils, % | 90 | – |
| Lymphocytes, % | 9 | – |
| Protein, mg/dL | 50 | 28 |
| Glucose, mg/dL | 61 | 75 |
| Gram stain | No organisms | No organisms |
| Culture | No growth | No growth |
| West Nile virus IgM | Negative | Not tested |
| Real-time RT-PCR for dengue, yellow fever, chikungunya, Zika, West Nile, and Japanese encephalitis viruses | Not detected | Not detected |
| Herpes simplex virus PCR | Negative | Not tested |
CSF = cerebrospinal fluid; IgM = immunoglobulin M; RT-PCR = reverse transcriptase polymerase chain reaction.
*
White blood cell differential was not performed.