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. Author manuscript; available in PMC: 2015 Oct 8.
Published in final edited form as: Annu Rev Neurosci. 2015 Apr 30;38:389–411. doi: 10.1146/annurev-neuro-071013-014243

Figure 2.

Figure 2

(a) Peak activation foci reported in prefrontal and anterior cingulate brain regions across neuroimaging studies of reward and self-regulation cited in this review are displayed on an inflated rendering of the medial and lateral cortical surfaces (Van Essen et al. 2012). Activations are broadly distributed throughout the PFC, and these widespread patterns of activation across studies have given rise to differential accounts of a preferential role for either the lateral PFC, VMPFC, or dACC in self-regulation. (b) When considered in the context of brain systems, however, activation foci cluster primarily into three subnetworks (as defined by Power et al. 2011): the frontoparietal system (yellow), the cingulo-opercular system (purple), and the default system (red). Abbreviations: dACC, dorsal anterior cingulate cortex; PFC, prefrontal cortex; VMPFC, ventromedial prefrontal cortex.